Qi JC, et al. - Researchers assessed the influence of continuous positive airway pressure (CPAP) on vascular endothelial growth factor (VEGF) levels in obstructive sleep apnea (OSA) patients, using Web of Science, Cochrane Library, PubMed, and Embase databases. The analysis of the summary estimates for CPAP therapy was carried out using standardized mean difference (SMD). The meta-analysis included six studies involving 392 patients. In OSA patients, a possible link was seen between CPAP therapy and improved endothelial function measured by VEGF. The CPAP efficacy was impacted by differences in age, body mass index, apnea–hypopnea index, CPAP therapy duration, sample size, and racial differences. For these subjects, the possible clinical importance of use of VEGF levels in cardiovascular disease assessment was suggested.