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Impact of body mass index on tumor recurrence among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma- A multi-institutional international analysis

European Journal of Surgical Oncology Mar 17, 2019

Merath K, et al. - In order to characterize the presentation and oncologic outcomes of intrahepatic cholangiocarcinoma (ICC) patients undergoing curative-intent resection according to category of body mass index (BMI), researchers assessed 790 patients who underwent resection of ICC as normal weight (BMI 18.5–24.9 kg/m2), overweight (BMI 25.0–29.9 kg/m2) and obese (BMI≥30 kg/m2) according to the World Health Organization definition. Out of 790 patients undergoing curative-intent resection of ICC in the analytic cohort, 50.5% had normal weight, 34.7% were overweight, and 14.8% were obese. Observations revealed an association of increasing BMI with incremental increases in the risk of recurrence following curative-intent resection of ICC. Increased BMI was an independent risk factor for tumor recurrence, on multivariable analysis.

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