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Impact of aspergillus precipitating antibody test results on clinical outcomes of patients with mycobacterium avium complex lung disease

Respiratory Medicine Apr 08, 2020

Shirai T, Furuuchi K, Fujiwara K, et al. - Researchers examined how results of Aspergillus precipitating antibody (APAb) test, a serodiagnostic test for pulmonary aspergillosis (PA), are associated with the clinical outcomes of patients with Mycobacterium avium complex lung disease (MAC-LD). Between 2007 and 2014, 131 patients who were newly diagnosed as having MAC-LD were checked for APAb at the time of diagnosis in this retrospective analysis. Among these patients, APAb test results were positive at the diagnosis of MAC-LD in 20 (15.3%) patients. More frequent reporting of underlying lung disease and more frequent development of PA was observed among APAb-positive patients with MAC-LD. APAb positivity was identified to be an independent negative prognostic factor in MAC-LD patients.

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