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Impact of arrhythmias on hospitalizations in patients with cardiac amyloidosis

The American Journal of Cardiology Dec 23, 2020

Thakkar S, Patel HP, Chowdhury M, et al. - Since there is a lack of data regarding the burden of arrhythmias in patients with cardiac amyloidosis (CA) during hospitalization, researchers used the National Inpatient Sample database from Jan 2016- Dec 2017, to determine the burden of arrhythmias. They compared CA patients with and without documented arrhythmias, in terms of patient features, results, and hospitalization expenses. All-cause mortality was the primary outcome, which was found to be significantly higher in CA patients with arrhythmia vs without(13.9% vs 5.3%). In CA cases with concurrent arrhythmia, the most commonly (72.2%) occurring arrhythmia was atrial fibrillation. Findings revealed a poorer prognosis in relation to the presence of arrhythmias in CA patients during hospital admission. Also, cases with a higher risk of heart failure exacerbation and death may be reflected by concurrent arrhythmia during hospital admission in CA patients.

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