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iGlarLixi: A new once-daily fixed-ratio combination of basal insulin glargine and lixisenatide for the management of type 2 diabetes

Diabetes Spectrum May 25, 2018

Hinnen D, et al. - In this review, researchers analyzed clinical evidence regarding dosing and administration of iGlarLixi, a titratable fixed-ratio combination of insulin glargine and the glucagon-like peptide (GLP)-1 receptor agonist lixisenatide that effectively lowers both fasting and postprandial glucose levels. In patients with type 2 diabetes requiring additional glycemic control, findings showed the efficacy as well as good tolerability of iGlarLixi as a treatment option with comparable or improved safety outcomes than its separate components. Adherence may be improved with iGlarLixi, attributed to its simple regimen and low rate of adverse effects. Improved adherence may lead to improved therapeutic outcomes.
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