Andeen NK, et al. - Given that IgA dominant membranoproliferative glomerulonephritis (MPGN) is a descriptive term for renal biopsies in which differential diagnoses of unusual IgA nephropathy (IgAN), infection-related GN, or other etiologies are considered, the researchers explored clinical and pathologic features of this finding. In this study, IgA dominant MPGN was seen in two clinical cohorts and this seemed to represent either a unique clinicopathologic entity with a poorer prognosis than IgAN or an aggressive variant of IgAN in subjects without chronic liver disease. Findings suggested that subjects with the chronic liver disease often have an infection and die within one year.