Kilic A, Seese L, Pagani F, et al. - Researchers used the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) to determine how adverse events (AEs) influence the development of subsequent AEs following left ventricular assist device (LVAD) surgery. Primary durable LVADs implanted between 2006 and 2016 were identified. Renal failure leading to hepatic dysfunction, respiratory failure resulting in renal failure, respiratory failure causing hepatic dysfunction, renal failure leading to respiratory failure, and renal failure leading to right ventricular assist device implant were all identified as the strongest positive links. Overall, most in‐hospital AEs post-LVAD implantation were shown to have a significant link with subsequent AEs development, with the most profound effect related to primary renal or respiratory failure, which were also found to be related to the lowest 1‐year survival. The greatest decreases in overall AE burden as well as subsequent mortality would possibly be achieved by targeting the decrease of renal or respiratory failure as the primary AE post-LVAD surgery.