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Hyperbaric oxygen therapy for radiation-induced tissue injury following sarcoma treatment: A retrospective analysis of a Dutch cohort

PLoS Neglected Tropical Diseases Jun 12, 2020

Generaal JD, Lansdorp CA, Boonstra O, et al. - As management of sarcomas with surgical resection combined with radiotherapy is frequently complicated by chronic wounds and late radiation tissue injury (LRTI), researchers here examined the use and results of hyperbaric oxygen therapy (HBOT) for managing radiation-induced complications following sarcoma treatment. Among 30 included patients who underwent treatment between 2006 and 2017 in one of the five centers of the Institute for Hyperbaric Oxygen in the Netherlands, 18 (60.0%) patients were treated for chronic wounds and 12 (40.0%) for LRTI. Outcomes support the safety and benefits of HBOT in treating chronic wounds and LRTI in the sarcoma population.

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