Woo JH, et al. - In this retrospective interventional case series, researchers assessed the outcomes and complications of hybrid Descemet membrane endothelial keratoplasty (H-DMEK) utilizing a Descemet stripping automated endothelial keratoplasty (DSAEK) pull-through donor inserter and donor stroma as a carrier. The sample consisted of eyes with bullous keratopathy (BK) and Fuchs endothelial corneal dystrophy (FECD), which had H-DMEK, performed using a bimanual pull-through technique using DSAEK-prepared donor stroma as carrier and the EndoGlide Ultrathin DSAEK donor insertion device. Of the 85 eyes from 79 individuals, 43.5% (n = 37) had BK, 28.2% (n = 24) had FECD while 24.7% (n = 21) had failed grafts. According to results, hybrid DMEK provides a controlled ‘pull-through’ technique of donor insertion in the ‘endothelium-in’ configuration, which can be helpful particularly in complicated eyes. In order to confirm the long-term endothelial cell loss and graft survival related to this technique, more studies are required.