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Household contact investigation for the detection of tuberculosis in Vietnam: Economic evaluation of a cluster-randomised trial

The Lancet Global Health Feb 21, 2019

Lung T, et al. - Researchers for the first time conducted an economic evaluation alongside the Active Case Finding in Tuberculosis (ACT2) trial to evaluate the costs and cost-effectiveness of an active case finding strategy in Vietnam, where tuberculosis [one of the top ten causes of death worldwide] is highly prevalent. Study participants (aged 15 years and older) with smear-positive pulmonary tuberculosis were selected to the trial if they lived with one or more other household members. Data reported that the incremental cost-effectiveness ratio per disability-adjusted life year (DALY) averted was $544. In a setting with a high prevalence of tuberculosis, active case finding has been shown to be highly cost-effective. Investment should be strongly supported in the wide-scale implementation of this programme in Vietnam.
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