Wong E, et al. - Given that estimation of glomerular filtration rate (eGFR) and albumin-creatinine ratio (ACR) is done for chronic kidney disease (CKD) risk staging and there is a high prevalence of CKD and a high risk of hospitalization in old age, researchers determined how the current CKD staging system is related to the all-cause hospitalization risk among older adults. From the Atherosclerosis Risk in Communities study, 4,766 participants were examined for CKD stage according to Kidney Disease Improving Global Outcomes (KDIGO) criteria, using creatinine-based eGFR and ACR. They noted 5,548 hospitalizations and CKD in 29% among participants. Reduced eGFR, elevated ACR, and KDIGO risk stages based on a combination of these measures were robust risk factors for hospitalization in older adults. Irrespective of the marker used to estimate GFR, the relationships were consistent, however, the use of cystatin C led to a substantially greater prevalence of CKD than the use of creatinine. Hospitalization rates exceeding 500 per 1,000 person-years were evident for older adults in the population with very high-risk stages of CKD.