High sensitivity C-reaction protein in HIV care: Tuberculosis diagnosis and short-term mortality in a cohort of Kenyan HIV patients in the DREAM program
International Journal of Infectious Diseases Jan 13, 2021
Ciccacci F, Welu B, Ndoi H, et al. - The role of HS-CRP in TB diagnosis and mortality predictivity in HIV + patients was examined via performing the IDEA-TB study. A total of 574 HIV + adult patients attending 3 DREAM Centers in Kenya who were suspected of having TB were enrolled. Researchers identified that challenges remains concerning TB diagnosis in HIV + patient. Mortality was not identified to be linked with any single factor, only the combination of malnutrition and elevated HS-CRP was highly predictive of death; the correlation was stronger in TB- patients (33.3% vs 1.0%).Findings suggest a possible value of HS-CRP for predicting early mortality in symptomatic patients.
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