Kwon JW, et al. - Researchers investigated whether asthma control could attenuate the future risk of asthma exacerbations (AEs) in patients with low forced expiratory volume in 1 s (FEV₁). In 565 patients with asthma from the COREA cohort, they assessed the future risks of AEs within six months according to Asthma Control Test (ACT) score and FEV₁. Despite ACT score ≥20 and asthma treatments, a higher risk of AEs was observed among patients with low FEV₁ vs those with near-normal FEV₁. Hence, there exists a need for treatment strategies to prevent AEs in high-risk asthmatic patients.