Glinz D, Bläsi C, Villiger A, et al. - This study was conducted to present hemodynamic profiles among treatment-naive hypertensive patients compared with normotensive controls and to explore if a hemodynamic-guided choice of therapy improves blood pressure (BP) control within 4 weeks. Researchers conducted exploratory post hoc analysis that used data of a randomized parallel-group trial including 80 outpatients with newly diagnosed arterial hypertension, randomized to four antihypertensive first-line monotherapies, and 20 age-matched and sex-matched normotensive controls. They assessed hemodynamic profiles at baseline and after four weeks of treatment. The data do not support the hypothesis that in newly diagnosed hypertensive outpatients, personalized treatment initiation based on hemodynamic profiles improves BP control.