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Glycated hemoglobin vs oral glucose tolerance test in the identification of individuals with prediabetes in Qatari population

BMC Endocrine Disorders Aug 28, 2019

Iskandar S, Migahid A, Kamal D, et al. - Given that individuals with prediabetes are at increased risk of future T2D and CVD vs normal glucose tolerance (NGT) people, researchers compared the ability of the oral glucose tolerance test (OGTT) and HbA1c to identify individuals in Qatar with prediabetes. For this retrospective analysis, 446 individuals without a history of T2D received 75-g OGTT and measurement of HbA1c. According to results, the agreement between OGTT and HbA1c was poor, though significant, in identifying individuals with prediabetes in individuals in Qatar. According to OGTT and HbA1c, only 56% of candidates had prediabetes or NGT. These findings show prediabetes individuals diagnosed with OGTT have a higher metabolic risk than those diagnosed with HbA1c and a higher risk of progression to T2D.

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