Lee MH, Vogrin S, Paldus B, et al. - In T1D adults with impaired awareness of hypoglycemia (IAH), researchers assessed exercise-related glucose and counterregulatory responses (CRR) utilizing hybrid closed-loop (HCL) insulin delivery to maintain glucose homeostasis. For this investigation, 12 candidates undertook 45-min high-intensity intermittent exercise (HIIE) and moderate-intensity exercise (MIE) in random order. According to results, HIIE induced increased levels of cortisol, noradrenaline, and lactate without differences in response to adrenaline, dopamine, growth hormone, or glucagon. Findings revealed that there is heterogeneity in CRR among IAH adults using HCL undertakings HIIE and MIE. Novel findings have been a preserved response to cortisol and variable responses to HIIE catecholamine.