Yadgir S, Johnson CO, Aboyans V, et al. - Researchers provide estimates of mortality, prevalence, and disability-adjusted life years (DALYs) for calcific aortic valve disease (CAVD), degenerative mitral valve disease (DMVD), and other non-rheumatic valvular heart disease for 195 countries and territories from 1990 to 2017, calculated as part of the Global Burden of Disease (GBD) 2017 study. Globally, 102,700 and 35,700 deaths were attributable to CAVD and DMVD, with 12.6 million and 18.1 million prevalent cases in 2017, respectively. Between 1990 and 2017, an increase in the number of DALYs for CAVD and DMVD by 123% and 64%, respectively, was revealed. Experts reported significant difference in the prevalence, mortality rate, and overall burden of these diseases by geography, with highest age-standardized DALY rates of CAVD calculated for high-income countries. Overall, CAVD and DMVD were identified as crucial causes of disease burden in older adults, as shown by these global and national estimates. To make progress toward decreasing, and ultimately removing, the burden of these highly treatable diseases, it is important to make attempts to better understand modifiable risk factors and enhance access to valve interventions.