Dah N, et al. - An analysis was conducted of the liver allograft complement fragment 4d (C4d) staining during acute antibody mediated rejection in formalin-fixed paraffin-embedded tissue across transplanted organs. In maximum laboratories, C4d staining reliably identified acute liver allograft antibody mediated rejection in formalin-fixed, paraffin-embedded tissues. Researchers recommended placing emphasis on portal veins and capillaries, sinusoids and central veins present in peripheral core needle biopsies, during the assessment. It was found that C4d staining in one organ did not always translate to staining in another.