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Global epidemiology of Neisseria gonorrhoeae in infertile populations: Systematic review, meta-analysis and metaregression

Sexually Transmitted Infections May 21, 2020

Chemaitelly H, Majed A, Abu-Hijleh F, et al. - Researchers sought to perform an in-depth systematic assessment of the global epidemiology of gonorrhoea infection in infertile populations. They identified 147 gonorrhoea prevalence studies from 56 countries. The pooled mean prevalence of current gonorrhoea infection was estimated globally at 2.2%; Africa has the highest prevalence at 5.0%. Analyses revealed several folds higher prevalence of gonorrhoea in infertile populations vs the general population, with even higher prevalence in women with tubal factor infertility and in individuals with secondary infertility. Findings thereby support the potential role of gonorrhoea in infertility and indicate that gonorrhoea transmission control may prevent some infertility.

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