Kapoor A, Foley G, Zhang N, et al. - Given a challenging risk-benefit assessment is implicated in the provision of anticoagulation (AC) for stroke prevention in long-term care (LTC) residents with atrial fibrillation (AF), researchers measured the link of geriatric conditions with discontinuation of AC in this retrospective cohort study performed in LTC facilities across the United States. Participants were 48,545 people in total who were living in LTC facilities in 2015 with AF. Recent fall, severe activity of daily living (ADL) dependency (21-28 on a 28-point scale), mobility impairment, cognitive impairment, body mass index (BMI) less than 18.5 kg/m², and weight loss (≥ 5% in 1 month or ≥ 10% in 6 months) were the six geriatric conditions the associations of which with discontinuation of AC was measured. A 1.9-fold rise in the odds of discontinuation was predicted by recent fall, whereas mobility and cognitive impairment only raised the odds by 14% to 17%. An increment in the odds of discontinuation by 55% to 68% was brought about by severe ADL dependency, BMI less than 18.5 kg/m², and weight loss of 10%, each. Overall, discontinuation of AC was predicted by many geriatric conditions but not by the CHA₂DS₂-VASc score.