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Gender-specific differences in survival and heart failure hospitalization after cardiac resynchronization therapy with or without defibrillation

Journal of the American Heart Association Nov 24, 2019

Leyva F, et al. - Researchers used a national database (Hospital Episode Statistics for England) to determine clinical consequences in females and males undergoing cardiac resynchronization therapy (CRT)-defibrillation or CRT-pacing in real-world clinical practice. Overall participants were 43,730 (women: 10,890 [24.9%]; men: 32,840 [75.1%]). They found that a longer life was lived by women vs men and there was less probability to be hospitalized for heart failure following CRT among women as compared with men. According to the findings, the superiority of CRT-defibrillation over CRT-pacing was evident in both genders in terms of survival and heart failure hospitalization. In addition, women without a history of myocardial infarction had the longest survival following CRT.
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