Mofrad MD, et al. - Researchers analyzed evidence from 16 relevant randomized clinical trials (RCTs) to determine how serum inflammatory biomarkers in adults are influenced by garlic supplementation. Only those RCTs that involved adults, reported the impact of garlic supplementation on inflammatory biomarkers vs a control group, and offered sufficient data on inflammatory biomarkers were included in this analysis. The included RCTs were identified from Scopus, PubMed, Google Scholar and Cochrane library databases. Garlic doses used in these studies ranged from 12 to 3,600 mg/d. The intervention was carried out from 2 to 52 weeks. The investigators noted reduced serum concentrations of C-reactive protein, tumor necrosis factor, and interleukin-6 in relation to garlic supplementation in adults, while no impact was evident with serum adiponectin and leptin.