Kanenawa K, Yamaji K, Tashiro H, et al. - Researchers assessed the predictive ability of frailty for bleeding following percutaneous coronary intervention (PCI). They prospectively evaluated frailty in 2,439 patients who were treated with PCI, by employing the Canadian Study of Health and Aging clinical frailty scale (CFS). The presence of Academic Research Consortium High Bleeding Risk (ARC-HBR) was evident in 47.3%, 83.2%, and 89.0% in the low CFS group, intermediate CFS group, and in the high CFS group, respectively. Experts consistently found the link of frailty with 1-year major bleeding in patients with and without high bleeding risk (HBR), this suggests that major bleeding post-PCI might be predicted by frailty per se on top of HBR criteria.