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Frailty among older adults with acute myocardial infarction and outcomes from percutaneous coronary interventions

Journal of the American Heart Association Sep 06, 2019

Damluji AA, Huang J, Bandeen-Roche K, et al. - From the Premier Healthcare Database, 469,390 adults (age ≥ 75 years) who were admitted with acute myocardial infarction (AMI) were examined for the prevalence of frailty. In addition, researchers examined how frailty influence interventions, and mortality. Frailty prevalence of 19% was identified. Frail vs nonfrail patients less frequently received the percutaneous coronary intervention (15% vs 33%) and much less frequently receive coronary artery bypass surgery (1% vs 9%). Individuals over age 85 years received far fewer interventions. They observed higher mortality during AMI admission in correlation with frailty. While there was a differential benefit of the interventions because of frailty, frail patients undergoing percutaneous coronary intervention and coronary artery bypass surgery had decreased hospital mortality relative to those frail patients who received no intervention. Findings support the judicial use of revascularization with percutaneous coronary intervention in frail older patients as it may confer an immediate survival benefit.
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