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Fractional esterification rate of cholesterol in high-density lipoprotein associates with risk of coronary heart disease

Lipids in Health and Disease Aug 31, 2017

Liu J, et al. – Researchers tried to find out the correlations of fractional esterification rate of cholesterol in high–density lipoprotein (FERHDL), assessed by the simple and precise HPLC method, with angiographically defined coronary heart disease (CHD) and its related risk factors in Chinese patients were evaluated. The results confirmed that fractional esterification rate of cholesterol in high–density lipoprotein significantly correlated with both HDL2–C and LDLb–C, and thus, is the predictor of lipoprotein distributions. In addition, after correcting for the presence of classic risk factors, fractional esterification rate of cholesterol in high–density lipoprotein was independently correlated with the presence of angiographically defined CHD.
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