Jiang Y, Wang D, Wang W, et al. - In this prospective, population-based cohort study, researchers examined the 5-year changes in static and dynamic anterior segment optical coherence tomography (AS-OCT) parameters and their predictors. The study sample consisted of people aged 50 years and older residing in the Liwan District, Guangzhou, China. Standardized AS-OCT scans were carried out under dark and light conditions in November 2008 and November 2013. For the analysis of horizontal AS-OCT images, customized software was used. In total, 186 individuals (mean age in 2008 was 64.7 ± 7.0 years) had AS-OCT twice, 5 years apart and were involved for analyses. During the 5-year follow-up, anterior chamber angle width reduced and the amount of light-to-dark changes declined. At baseline, individuals with greater height, wider angle width and thicker iris have greater angle narrowing at follow-up.