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Femoral vs nonfemoral subclavian/carotid arterial access route for transcatheter aortic valve replacement: A systematic review and meta‐analysis

Journal of the American Heart Association Oct 19, 2020

Faroux L, Junquera L, Mohammadi S, et al. - Researchers compared transcarotid/transsubclavian vs transfemoral transcatheter aortic valve replacement recipients, in terms of the risk of 30‐day complications as well as mortality. They analyzed 20 studies, with 79,426 patients (16 studies) and 3,992 patients (4 studies) for ascertaining the unadjusted as well as adjusted effect of the arterial approach, respectively. According to findings, an elevated risk of stroke was observed in relation to transcarotid and transsubclavian approaches for transcatheter aortic valve replacement vs the transfemoral approach. However, there was no link of these nonfemoral arterial alternative accesses with an elevated risk of 30‐day mortality, bleeding, or vascular complication when confounding factors were taken into account.

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