Features distinguishing clinically amyopathic juvenile dermatomyositis from juvenile dermatomyositis
Rheumatology Jul 20, 2018
Mamyrova G, et al. - Authors evaluated the features of clinically amyopathic JDM (CAJDM), in which patients have characteristic rashes with little to no evidence of muscle involvement, to ascertain whether or not this is a distinct phenotype from JDM. As per data, CAJDM often have p155/140 (transcriptional intermediary factor 1) autoantibodies, have fewer systemic manifestations and receive less therapy and this may distinguish CAJDM from JDM. On multivariable modelling, a lower skeletal score and less frequent myalgias were revealed as the most important factors in distinguishing CAJDM from JDM.
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