Grimm A, et al. - In this investigation, researchers ascertained if changes in thigh soft tissue composition and changes in muscle size and composition resulting from physical training could be detected with Dixon magnetic resonance imaging (MRI). A young and healthy population of subjects (n = 21, 29 ± 5 years) was divided into a strength training (G_t, 11 subjects) and a control group (G_c, 10 subjects). In muscle area and muscular fat, Dixon MRI is capable to measure training-related changes. Both parameters correlate with the function of the muscle. Investigators found that muscle area per se does not always mirror functional parameters. Multivariate muscle parameter models should be investigated in the future due to the complex interaction of muscle volume, muscle structure, and inter- and intramuscular coordination during muscle performance.