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Factors related to primary cancer death and non‐primary cancer death in patients treated with stereotactic body radiotherapy for pulmonary oligometastases

Cancer Medicine Oct 13, 2020

Yamamoto T, Niibe Y, Matsumoto Y, et al. - Researchers sought to ascertain the cumulative incidences of cancer‐specific death (CSD) and non‐cancer‐specific death (non‐CSD) following stereotactic body radiotherapy (SBRT) for pulmonary oligometastases, as well as exploring the prognostic factors. For this purpose, they used data for 1,326 patients taken from a large survey of those who had SBRT for pulmonary oligometastases. The occurrence of CSD and non‐CSD was noted in 375 and 109 patients, respectively. The factors related to the incidence of CSD in multivariate analyses included performance status, oligometastatic state, and maximum tumor diameter, while the incidence of non‐CSD was shown to be associated with age, gender, performance status, and irradiated tumor‐located lung lobe. Findings revealed CSD as the predominant cause of death, but non‐CSD was not rare following SBRT. Different prognostic factors for CSD and non‐CSD were evident and their understanding would aid treatment.

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