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Extragenital Mycoplasma genitalium infections among men who have sex with men

Sexually Transmitted Infections Jun 22, 2019

Latimer RL, et al. - Researchers investigated the percentage of rectal Chlamydia trachomatis (CT) and rectal Neisseria gonorrhoeae (NG) infections in men who have sex with men (MSM) who are coinfected with rectal Mycoplasma genitalium (Mgen). In addition, they sought for the percentage of MSM with Mgen detected in the pharynx. At Melbourne Sexual Health Centre in Australia, MSM who had positive rectal swabs for CT (n=212) or NG (n=212) were collected, as were pharyngeal samples (n=480) from MSM, and both wre tested for Mgen using the Aptima Mycoplasma genitalium Assay (Hologic, San Diego). Data revealed the presence of undiagnosed Mgen in one in seven MSM treated for rectal CT or rectal NG, which could potentially be exposed to azithromycin during treatment of these other STIs. MSM with rectal CT/Mgen coinfection vs those with rectal CT monoinfection had more sexual partners. MSM with rectal NG/Mgen coinfection vs those with rectal NG monoinfection were more frequently HIV-positive. MSM with rectal CT/Mgen coinfection vs MSM with rectal NG/Mgen coinfection more frequently reported using pre-exposure prophylaxis. Uncommon occurrence of pharyngeal Mgen was noted. They noted pharyngeal Mgen in association to having a rectal STI, and in a marginal link with being HIV-positive.

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