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Excess risk for atherosclerotic cardiovascular outcomes among US adults with HIV in the current era

Journal of the American Heart Association Jan 08, 2020

Rosenson RS, Hubbard D, Monda KL, et al. - Given a higher risk for atherosclerotic cardiovascular disease (ASCVD) has been reported in the 2000s in adults with HIV vs those without HIV, and the presence of uncertainty regarding whether this excess risk still exists in the US given shifts in antiretroviral treatments and improved statin use, researchers compared US adults aged ≥ 19 years with and without HIV, in terms of the risk for ASCVD events. These people had commercial or supplemental Medicare health insurance between January 1, 2011, and December 31, 2016. For ASCVD, myocardial infarction, stroke, and lower extremity artery disease hospitalizations, the multivariable-adjusted hazard ratio (95% CI) were estimated to be 1.29 (1.18–1.40), 1.26 (1.13–1.39), 1.30 (1.11–1.52), and 1.46 (1.11–1.92), respectively, when beneficiaries with HIV were compared with those without HIV. Overall, a higher ASCVD risk was reported in adults with HIV in the United States, relative to their counterparts without HIV.
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