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Evaluation of hypoglossal nerve stimulation treatment in obstructive sleep apnea

JAMA Otolaryngology-Head & Neck Surgery Dec 08, 2019

Kent DT, et al. - In this investigation involving 584 individuals [mean (SD) age was 58.5 (11.0) years], researchers explored the correlation of hypoglossal nerve stimulation with obstructive sleep apnea severity, daytime sleepiness, and sleep-related quality of life. The primary outcome was severity of obstructive sleep apnea. Findings suggested an association of greater improvement in the postoperative AHI with a higher preoperative AHI, older patient age, and lower BMI. The AHI was statistically higher at 12 months than at 6 months after adjusting for these variables and considering all patients in the analysis. According to results, hypoglossal nerve stimulation was correlated with clinically significant improvements in obstructive sleep apnea severity, daytime sleepiness, and sleep-related quality of life, and patient features were related to the degree of improvement.
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