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Evaluation of adherence and anti-infective properties of probiotic Lactobacillus fermentum strain 4-17 against Escherichia coli causing urinary tract infection in humans

Microbial Pathogenesis Apr 25, 2019

Falah F, et al. - Researchers assessed probiotic properties of Lactobacillus fermentum strain 4-17, isolated from kashkineh, an Iranian cereal fermented food, to see if it had any value for fighting GI infections. L. fermentum strain 4-17 showed good adaptation to gastrointestinal conditions. Its adhesion level to human colon adenocarcinoma Caco-2 cells was 8.5%, and appropriate anti-adhesive properties (including competition, inhibition and replacement properties) against human pathogenic bacteria were noted with this strain. They observed the satisfactory anti-infective impact of this strain against Escherichia coli. Findings thereby support further examination of L. fermentum strain 4-17 for its valuable effects and suggest its introduction as a novel candidate for probiotic control of GI infection disease.

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