Nickbakhsh S, Ho A, Marques DFP, et al. - In view of the essence of setting-specific epidemiological data for public health preparedness for coronavirus disease 2019 (COVID-19), researchers sought to delineate the epidemiology of seasonal coronaviruses (sCoVs) and other cocirculating viruses in the West of Scotland, UK. Routine diagnostic data for > 70,000 episodes of respiratory illness tested molecularly for multiple respiratory viruses between 2005 and 2017 were analyzed. CoV-229E, CoV-OC43 and CoV-NL63 differed in statistical associations with patient age and gender. Furthermore, no concurrent occurrence of the timing and magnitude of sCoV outbreaks was observed and no coinfections were reported. When considering other cocirculating respiratory viruses, evidence was gained of positive, rather than negative, interactions with sCoVs. Findings thereby emphasize the significance of considering cocirculating viruses in the differential diagnosis of COVID-19.