Rennert-May E, et al. - Researchers sought to provide an updated data on the rates of cardiac implantable electronic device (CIED) infection in the United States. Further, they inscribed if and how these rates are influenced by different variables including gender, length of stay (LOS), and costs. The 2016 Healthcare Care and Utilization Project National Inpatient Sample database was assessed for retrieving data for this work and CIED infections were tracked using International Classification of Diseases, Tenth Revision codes. Among 191,610 CIED implantations identified, 8,060 infections (4.2%) were reported. The majority of patients with CIED infection were observed to have ≥ 3 comorbidities that were linked with increased costs and LOS. Relative to males, females had decreased LOS and costs. Findings thereby emphasize recognizing patients with increased numbers of comorbidities and managing them carefully peri-CIED implantation given their raised risk of infection and use of healthcare resources.