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Epidemiology and risk factors for mortality in bloodstream infections: A single-center retrospective study in Japan

American Journal of Infection Control Sep 04, 2018

Hattori H, et al. - As only a few published data are available on the morbidity and mortality of bloodstream infections (BSIs) in Japan, researchers performed a single-center study determining the epidemiology of BSIs, the involvement of antimicrobial resistance, and the factors that influence patient prognosis. They analyzed 2,105 patients who were found to have positive blood cultures at a tertiary teaching hospital between January 2012 and December 2016. Among these, death was reported for 319 patients. Over the 5-year study period, they noted the 30-day mortality rate of 15.2%. BSIs caused by yeasts were noted to be independently correlated with 30-day mortality. BSIs caused by extended-spectrum beta lactamase–producing gram-negative bacteria were correlated with significantly higher 30-day mortality rate compared to those caused by nonproducing bacteria.
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