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Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center

BMC Infectious Diseases Jan 29, 2019

Kangbai JB, et al. - Researchers sought to determine the effects of Ebola Virus Disease (EVD) on children via performing an observational retrospective analysis of medical data of all laboratory-confirmed pediatric EVD patients below 15 years of age who were admitted at the 34 Military Hospital Ebola Treatment Center (ETC) in Wilberforce, Sierra Leone between June 2014 to April 2015. EVD infection was slightly more prevalent among females than males. Higher Case Fatality Rates (CFRs) were noted for EVD cases below 5 years of age, as well as for those with difficulty in breathing, difficulty in swallowing, signs of conjunctivitis and those with Stage 3 EVD infection at the time of admission compared to the other pediatric EVD cases without these criteria. Additionally, higher tendency to have increased odds of dying during EVD treatment was noted among male pediatric EVD patients, pediatric EVD patient who reported abdominal pain, difficulty in breathing, vomiting and showed signs of conjunctivitis at the time of admission.
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