Epicardial adipose tissue thickness as an independent predictor of ventricular tachycardia recurrence following ablation
Heart Rhythm Jun 19, 2019
Shamloo AS, et al. - Among consecutive patients (n=61, mean age=62.0±13.9) undergoing ventricular tachycardia (VT) ablation with pre-procedural cardiovascular magnetic resonance imaging (CMR), researchers sought to determine the link between epicardial adipose tissue (EAT) and post-ablation VT recurrence. They measured EAT thickness by means of CMR in the right and left atrioventricular grooves (AVGs), right ventricular free wall, anterior, inferior, and superior interventricular grooves. For predicting VT recurrence, the best cut-off points were calculated as 15.5 mm and 11.5 mm for the right AVG (area under ROC curve=0.74) and for the left AVG (area under ROC curve=0.72), respectively. After adjustment for covariates, only pre procedural right AVG-EAT independently predicted VT recurrence, in the multivariate Cox regression analysis. To risk stratify post-ablation VT recurrence, a novel possible imaging marker is suggested in this study. Findings are suggestive of a possible association of a higher EAT with VT recurrence.
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