Shapira U, et al. - By analyzing data of 18,089 apparently healthy individuals recruited for the Tel Aviv Medical Center Inflammation Survey, researchers determined the influence of blood eosinophil levels on lung function trajectories. Participants with normal and those with abnormal lung function were compared with respect to blood eosinophil levels. Using multivariate regression, they evaluated the OR of forced expiratory volume in 1 second (FEV₁) deterioration based on baseline eosinophils in 4,141 subjects with normal lung function over 4 years. Even in apparently healthy subjects, pulmonary function test (PFT) deterioration could be predicted by higher blood eosinophil levels. This was suggestive of a possible benefit from frequent lung function assessment in these subjects.