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Endophthalmitis rates among patients receiving intravitreal anti-VEGF injections: a USA claims analysis

Clinical Ophthalmology Sep 07, 2018

Kiss S, et al. - In order to determine the risk factors associated with developing endophthalmitis, and examine the claims for subsequent treatment, researchers compared the rates of endophthalmitis claims (sterile and infectious) following intravitreal (IVT) anti-vascular endothelial growth factor (VEGF) injections. Findings suggested a very low rate of endophthalmitis but it was higher after IVT injection with aflibercept vs both bevacizumab and ranibizumab in patients with neovascular age-related macular degeneration (nAMD). Injectable antibiotics were received by 38.6% of cases, injectable steroids were received by 15.3% and 30.3% underwent vitrectomy within 14 days after endophthalmitis.
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