Chen KH, et al. - In patients with retina vein occlusion (RVO), a visual-threatening retinal disease that causes irreversible impaired quality of life, researchers measured the serum oxidative biomarker to assess further physical response. Findings suggested an increase in the serum level of malondialdehyde (MDA), 8-hydroxy-2-deoxyguanosine (8OHdG) and hydrogen peroxide in patients with RVO. The increase in MDA, 8OHdG and hydrogen peroxide among these indicates an increase in serum oxidative stress in RVO patients. All enzymes related reactive oxygen species scavenge have been decreased. Focal RVO can, therefore, increase systemic oxidative stress in serum.