• Profile
Close

Elevated thrombospondin-2 contributes to delayed wound healing in diabetes

Diabetes Aug 13, 2019

Kunkemoeller B, Bancroft T, Xing H, et al. – In this study, researchers determined if the expression of thrombospondin-2 (TSP2) is correlated with delayed healing in diabetes. They discovered that TSP2 expression was raised in diabetic mice as well as the skin from diabetic patients. They developed a novel diabetic TSP2-deficient model to determine the contribution of TSP2 to impaired healing in diabetes. In order to increase the expression of TSP2, high glucose mechanistically increased activation of the hexosamine pathway and NF-κB signaling. According to findings, the expression of TSP2 induced by hyperglycemia may contribute to impaired diabetes healing.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay