Patzelt J, et al. - Using the MitraClip system, researchers examined the impacts on long-term outcome of residual mitral regurgitation (MR) and mean mitral valve pressure gradient (MVPG) after percutaneous edge-to-edge mitral valve repair. For this investigation, they analyzed 255 patients who had percutaneous edge-to-edge mitral valve repair. In patients with degenerative MR only, the authors discovered a rise in mean MVPG following percutaneous mitral valve repair could predict the clinical result. There appears to be no adverse impact of increased MVPG on clinical outcome in patients with functional MR. In the patient cohort with degenerative MR, MVPG >4.4 mm Hg after MitraClip implantation was predictive of clinical outcome. MVPG >4.4 mm Hg was not linked to increased clinical events in the patient cohort with functional MR.