Elevated eosinophils as a feature of inflammation associated with hypertension in virally suppressed people living with HIV
Journal of the American Heart Association Feb 26, 2020
Masenga SK, Elijovich F, Hamooya BM, et al. - Whether chronic inflammation may contribute to hypertension in people living with HIV (PLWH), was investigated in this study including a cohort comprising 70 PLWH (44% hypertensive) on a long-term single antiretroviral therapy regimen. The levels of inflammatory cytokines, including tumor necrosis factor-α receptor 1, interleukin-6, interleukin-17, interleukin-5, intercellular adhesion molecule 1 and macrophage inflammatory protein-1α, were found to be higher among hypertensive PLWH. The circulating eosinophils continued to be significantly related to hypertension, following adjustment for age, gender, and fat mass index. Considering these outcomes, experts evaluated the link of eosinophils and hypertension in 2 cohorts including 50 and 81,039 similar HIV-negative individuals; although a link of eosinophil count with prevalent hypertension was evident, this association was abrogated by body mass index. A unique linkage between immune status and cardiovascular physiological features in HIV infection was suggested.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries