Yan W, et al. - Because elevated D-dimer levels have been associated with poor outcomes in patients with cardiovascular disease, researchers examined this connection in elderly patients with chronic heart failure (CHF). They analyzed 1,355 elderly patients who were admitted with CHF. D-dimer levels were measured in all patients within the first 24 hours of admission. To evaluate the variables associated with chronic kidney disease (CKD), they used a multivariate logistic regression model. To assess the multivariable relationship between the D-dimer and subsequent all-cause death, Cox regression analysis was used. The D-dimer was identified as a risk factor for CKD in the multiple logistic regression analysis. According to findings, measurement of D-dimer levels in elderly patients with CHF may help to risk stratify these patients, and high D-dimer levels may be considered a warning sign to intensify therapy.