Yoon HK, Lee HC, Kang P, et al. - Researchers explored how landmark-based subclavian vein catheterization is impacted by the cross-sectional area of the subclavian vein (csSCV), by performing this randomized controlled study. A two-stage protocol was implemented. Experts measured the csSCV, during stage I, in 17 patients placed in the supine, 20° ipsilateral tilt, and 20° contralateral tilt positions in a random order. Landmark-based subclavian vein catheterization was randomly done, during stage II, in patients placed in either the supine (group S, n = 107) or the ipsilateral tilt (group I, n = 109) position. The csSCV in stage I and the primary venipuncture success rate in stage II was the primary outcome measure. As per the findings, among patients placed in the ipsilateral tilt, vs in the supine position, there was a significantly larger csSCV, however, the difference did not lead to better clinical performance of landmark-based subclavian vein catheterization.