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Effects of flavanol-rich dark chocolate on visual function and retinal perfusion measured with optical coherence tomography angiography: A randomized clinical trial

JAMA Ophthalmology Oct 03, 2019

Siedlecki J, et al. - In this randomized, masked double-blind crossover clinical trial, researchers evaluated the impacts of dark chocolate flavanols on subjective visual function and retinal perfusion objectively quantified on optical coherence tomography (OCT) angiography. Twenty-two healthy candidates at the Department of Ophthalmology, Ludwig Maximilians-University Munich, Germany, in July 2018, were analyzed. To consume 20 g of dark chocolate comprising 400 mg of flavanols or 7.5 g of milk chocolate, candidates were randomized. Visual function and retinal perfusion were evaluated on OCT angiography 2 hours later. Dark chocolate on OCT angiography was not shown to boost visual acuity, contrast sensitivity, or retinal perfusion relative to ingestion of milk chocolate. Unlike a prior trial reporting positive impacts on visual function of dark chocolate flavanol, this likewise sized trial did not discover any impacts on subjective (visual function) or objective (retinal perfusion) endpoints.
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