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Effect of sun exposure vs oral vitamin D supplementation on serum 25-hydroxyvitamin D concentrations in young adults: A randomized clinical trial

Clinical Nutrition Mar 28, 2019

Joh HK, et al. - Because vitamin D inadequacy is associated with a wide range of diseases, researchers investigated the impact of sun exposure vs oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in young adults in this 8-week randomized, placebo-controlled clinical trial. Specifically, they compared vitamin D-deficient adults in Seoul, Korea, with respect to changes in serum 25OHD concentrations. Participants were assigned to sun exposure (daily ≥ 20–30 minutes around noon; n=50), oral vitamin D3 (500 IU/d; n=50), and control (placebo; n=50) groups. They found that sun exposure and oral vitamin D3 increased serum 25OHD concentrations effectively. They observed that enhanced sun exposure and 500 IU/d of oral vitamin D3 supplementation increased serum 25OHD concentrations significantly. However, the sun exposure protocol was not as effective as supplementation with oral vitamin D3 at 500 IU/d. Changes in cardiometabolic markers in all groups were mostly insignificant.

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