Effect of statin intensity on the risk of epilepsy after ischaemic stroke: Real-world evidence from population-based health claims
CNS Drugs Apr 10, 2018
Lin FJ, et al. - Researchers studied Taiwanese health claims (2003–2013) to investigate the association between statin use, including timing of prescribing (pre-stroke vs post-stroke), type (lipophilicity, intensity of therapy) and dose intensity, and risk of developing post-stroke epilepsy (PSE). A significantly reduced risk of developing PSE was observed with post-stroke statin use, but not with pre-stroke statin use. They also noted a dose-response correlation was also observed between PSE risk reduction and quartiles of the statin cumulative defined daily dose.
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